Biography

A practicing acute care pediatric nurse practitioner in hematology-oncology, Keim-Malpass integrates clinical expertise with research at the intersection of health economics, artificial intelligence, and implementation science. Her federally funded program of research focuses on improving care for children and families facing serious illness, with particular emphasis on pediatric sepsis, acute myeloid leukemia, end-of-life trajectories, and cancer survivorship. She has led NIH- and AHRQ-funded projects advancing microsimulation models, decision-support tools, and health communication strategies to reduce uncertainty and support patient- and family-centered decision-making.

A Fellow of the American Academy of Nursing, Keim-Malpass is recognized nationally for advancing equitable innovation in precision medicine, digital health, and nursing science.

Education

  • Universitat Pompea Fabra/Barcelona School of Management - MSc, Health Economics & Pharmacoeconomics (2021)
  • Johns Hopkins University - MSc, Regulatory Science (Biotechnology) (2018)
  • Wake Forest University School of Medicine - Post-Doctoral Research Fellow, Department of Social Sciences & Health Policy (2013)
  • University of Virginia - PhD, Nursing (2011)
  • University of Virginia - MSN, Clinical Nurse Leader (2008), Pediatric Nurse Practitioner - Acute Care (2022)
  • University of Virginia - MS, Health Evaluation Sciences (2005)
  • Wake Forest University - BS, Biology, minor Chemistry (2004)

Certifications

  • Acute Care Certified Pediatric Nurse Practitioner (CPNP-AC)

Recent Grants

  • (2022-2025) AHRQ R01 (Keim-Malpass, mPI (contact)). Predictive Monitoring: IMPact of Real-time Predictive Monitoring in Acute Care Cardiology Trial (PM-IMPACCT)
  • (2020-2023) Gordon and Betty Moore Foundation (Keim-Malpass, PI). Betty Irene Moore Nurse Innovator Fellow. Novel Computational Approaches to Uncover Trajectories of Sepsis for Children.
  • (2020-2021) National Science Foundation (NSF) (Keim-Malpass, PI). Shared decision models to guide drug allocation during a pediatric chemotherapy shortage.
  • (2020-2022) NIH/NINR R56. (Lindley, PI). Effectiveness of End-of-Life Strategies to Improve Health Outcomes and Reduce Disparities in Rural Appalachia. Role: Co-I
  • (2019-2022) NIH/NICHD R03 (Letzkus, PI). NEO rehab program for premature infants at risk of cerebral palsy.  Role:  Co-I.
  • (2018-2020) NIH/NINR R21 (Keim-Malpass, Co-PI/Valdez, Co-PI). Self Management Characterization for Children with Medical Complexity and their Social Networks.  Role: Co-PI.
  • (2018-2022) NIH/NINR R01 (Lindley, PI).  Effectiveness of Concurrent care to Improve Pediatric and Family Outcomes at the End of Life.  Role:  Co-I
  • (2018-2019) University of Virginia 3Cavs.  (McManus, PI). HIV and Health Insurance following the Affordable Care Act.  Role:  Co-I.
  • (2018-2019) University of Virginia Global Infectious Disease Institute (Moore, PI). A planning grant proposal to support a clinical trial of empiric anti-Mycobacterium tuberculosis therapy for HIV-infected patients with sepsis in Sub-Saharan Africa.  Role: Co-PI
  • (2017-2020) Translational Health Institute of Virginia Scholars Program (Keim-Malpass, PI). A Pragmatic Clinical Trial Evaluating Impact of Continuous Predictive Monitoring on a Nurse-Driven Outcome in a Dynamic Intensive Care Setting.
  • (2017-2019) Lucile Packard Foundation for Children's Health (Keim-Malpass, PI).   Analysis of Home and Community-Based Waiver Services Among Children with Medical Complexity:  Are States Providing Family-Centered Care?
  • (2017-2018)American Cancer Society IRG Grant (Keim-Malpass, PI).  Assessment of accrual success for early phase pediatric oncology therapuetic trials.
  • (2017-2018) University of Virginia Cancer Control and Population Health.  Towards family-centered clinical trials for young people. 
  • (2016-2017) University of Virginia, School of Nursing, Oscar and Ruth Lanford Research Award (Keim-Malpass and Vergales, Co-PI).  Assessing the Feasibility and Acceptability of Technology-Enhanced Home Monitoring for the Pediatric Single Ventricle Cardiology Population:  Opportunities for Family Engagement.
  • (2016-2017) Merck and Company (PI: R Balkrishnan). Exploring Issues related to Vaccine Hesitancy in HPV: Development of a cancer risk-focused educational intervention. Role:  Co-I
  • (2016).  Virginia Department of Health, Office of Family Health Services, Division of Child and Family Health and Children/Youth with Special Health Care Needs. (Co-PIs:  Keim-Malpass & DeGuzman). Evaluation of Child Development Centers in the Commonwealth of Virginia.
  • (2015-2017).  University of Virginia, Cancer Prevention and Control Grant.  (PI: DeGuzman). A Pilot Study to Explore the Survivorship Needs of Rural, Low-Income Cancer Patients.  Role:  Co-I.
  • (2014-2015). NIH/NCI P30CA044579 (PI on core grant: T. Loughran, MD, University of Virginia School of Medicine, Project PI for P30:  Keim-Malpass).  Building a foundation for increased HPV vaccination rates in the University of Virginia Cancer Center’s Catchment area:  Focus on health communication and policy implications of adolescent HPV immunization among medically underserved communities.

Clinical Focus

Pediatric, adolescent, and young adult oncology; pediatric critical care; pediatric medical complexity; breast oncology.